and Robert De Niro
are in negotiations to star in Nancy Meyers' The Intern which Worldview Entertainment's Scott Rudin is producing, reports Variety
The story follows tells of the owner of a successful fashion website who bonds with an aged intern (played by De Niro) who has been hired by her company.
Meyers directed and wrote Jack Nicholson and Diane Keaton starrer Something's Gotta Give, with previous credits including The Parent Trap and Charles Shyer's Father of the Bride starring Steve Martin, and also Diane Keaton.
Witherspoon was last seen in Mud alongside Matthew McConaughey. Next year she's with Colin Firth, World War Z star Mireille Enos and Chronicle's Dane DeHaan in Atom Egoyan's Devil's Knot crime drama.
De Niro is in David O. Russell's American Hustle alongside Christian Bale, Bradley Cooper, Amy Adams, Jennifer Lawrence and Jeremy Renner. That film hits theaters on December 18th this year. After that, he's slugging it out with Sylvester Stallone in the Grudge Match comedy from director Peter Segal, also with Kim Basinger, Kevin Hart and Jon Bernthal.